| Week 1 | ||||||
| Day | Time | Network | Visitor | Score | Home | Score |
| Thursday, Sept 4 | 7 p.m. | NBC | Washington Redskins | 7 | New York Giants | 16 |
| Sunday, Sept 7 | 1 p.m. | CBS | Cincinnati Bengals | 10 | Baltimore Ravens | 17 |
| Sunday, Sept 7 | 1 p.m. | CBS | New York Jets | 20 | Miami Dolphins | 14 |
| Sunday, Sept 7 | 1 p.m. | CBS | Kansas City Chiefs | 10 | New England Patriots | 17 |
| Sunday, Sept 7 | 1 p.m. | CBS | Houston Texans | 17 | Pittsburgh Steelers | 38 |
| Sunday, Sept 7 | 1 p.m. | CBS | Jacksonville Jaguars | 10 | Tennessee Titans | 17 |
| Sunday, Sept 7 | 1 p.m. | FOX | Detroit Lions | 21 | Atlanta Falcons | 34 |
| Sunday, Sept 7 | 1 p.m. | FOX | Seattle Seahawks | 10 | Buffalo Bills | 34 |
| Sunday, Sept 7 | 1 p.m. | FOX | Tampa Bay Buccaneers | 20 | New Orleans Saints | 24 |
| Sunday, Sept 7 | 1 p.m. | FOX | St. Louis Rams | 3 | Philadelphia Eagles | 38 |
| Sunday, Sept 7 | 4:15 p.m. | FOX | Dallas Cowboys | 28 | Cleveland Browns | 10 |
| Sunday, Sept 7 | 4:15 p.m. | FOX | Carolina Panthers | 26 | San Diego Chargers | 24 |
| Sunday, Sept 7 | 4:15 p.m. | FOX | Arizona Cardinals | 23 | San Francisco 49ers | 13 |
| Sunday, Sept 7 | 8:15 p.m. | NBC | Chicago Bears | 29 | Indianapolis Colts | 13 |
| Monday, Sept 8 | 7 p.m. | ESPN | Minnesota Vikings | 19 | Green Bay Packers | 24 |
| Monday, Sept 8 | 10:15 p.m. | ESPN | Denver Broncos | 41 | Oakland Raiders | 14 |
NFL Schedule: Week 1
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