| Week 16 | ||||||
| Day | Time | Network | Visitor | Score | Home | Score |
| Thursday, Dec. 18 | 8:15 p.m. | NFLN | Indianapolis Colts | Jacksonville Jaguars | ||
| Saturday, Dec. 20 | 8:15 p.m. | NFLN | Baltimore Ravens | Dallas Cowboys | ||
| Sunday, Dec 21 | 1 p.m. | CBS | Cincinnati Bengals | Cleveland Browns | ||
| Sunday, Dec 21 | 1 p.m. | CBS | Buffalo Bills | Denver Broncos | ||
| Sunday, Dec 21 | 1 p.m. | CBS | Miami Dolphins | Kansas City Chiefs | ||
| Sunday, Dec 21 | 1 p.m. | CBS | Pittsburgh Steelers | Tennessee Titans | ||
| Sunday, Dec 21 | 1 p.m. | FOX | Philadelphia Eagles | Washington Redskins | ||
| Sunday, Dec 21 | 1 p.m. | FOX | Arizona Cardinals | New England Patriots | ||
| Sunday, Dec 21 | 1 p.m. | FOX | New Orleans Saints | Detroit Lions | ||
| Sunday, Dec 21 | 1 p.m. | FOX | Atlanta Falcons | Minnesota Vikings | ||
| Sunday, Dec 21 | 1 p.m. | FOX | Carolina Panthers | New York Giants | ||
| Sunday, Dec 21 | 1 p.m. | FOX | San Francisco 49ers | St. Louis Rams | ||
| Sunday, Dec 21 | 4:05 p.m. | CBS | New York Jets | Seattle Seahawks | ||
| Sunday, Dec 21 | 4:05 p.m. | CBS | Houston Texans | Oakland Raiders | ||
| Sunday, Dec 21 | 8:15 p.m. | NBC | San Diego Chargers | Tampa Bay Buccaneers | ||
| Monday, Dec. 22 | 8:30 p.m. | ESPN | Green Bay Packers | Chicago Bears | ||
NFL Schedule: Week 16
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